• Article  

      Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms 

      Liu, J.; Burdette, J. E.; Xu, H.; Gu, C.; Van Breemen, R. B.; Bhat, K. P. L.; Booth, N.; Constantinou, Andreas I.; Pezzuto, J. M.; Fong, H. H. S.; Farnsworth, N. R.; Bolton, J. L. (2001)
      Eight botanical preparations that are commonly used for the treatment of menopausal symptoms were tested for estrogenic activity. Methanol extracts of red clover (Trifolium pratense L.), chasteberry (Vitex agnus-castus ...
    • Article  

      Trifolium pratense (red clover) exhibits estrogenic effects in vivo in ovariectomized sprague-dawley rats 

      Burdette, J. E.; Liu, J.; Lantvit, D.; Lim, E.; Booth, N.; Bhat, K. P. L.; Hedayat, S.; Van Breemen, R. B.; Constantinou, Andreas I.; Pezzuto, J. M.; Farnsworth, N. R.; Bolton, J. L. (2002)
      Studies were conducted using an ovariectomized rat model to determine the estrogenic and antiestrogenic activity of Trifolium pratense L. (red clover) extracts. A red clover extract, standardized to contain 15% isoflavones ...